| Primary Identifier | MGI:1351466 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 27260 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phosphatidylinositol-3,4-bisphosphate binding activity; phosphatidylinositol-3,5-bisphosphate binding activity; and phosphatidylinositol-3-phosphate binding activity. Involved in actin cytoskeleton organization and positive regulation of plasma membrane bounded cell projection assembly. Acts upstream of or within positive regulation of cell projection organization. Located in membrane. Is active in plasma membrane. Orthologous to human PLEK2 (pleckstrin 2). PHENOTYPE: Knockout mice exhibit mild anemia with aging, mild ineffective erythropoiesis, slightly enlarged spleen and increased sensitivity of peripheral red blood cells to oxidative damage. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
