Primary Identifier | MGI:1354730 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 50779 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activator activity and protein domain specific binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway; positive regulation of GTPase activity; and positive regulation of neuron differentiation. Predicted to be located in cytosol and membrane. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and neuron projection. Is expressed in atrioventricular bundle; impulse conducting system; and sinoatrial node. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human RGS6 (regulator of G protein signaling 6). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased heart rate and abnormal impulse conducting system conduction. [provided by MGI curators] |