| Primary Identifier | MGI:1915831 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 68581 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein transmembrane transporter activity and syntaxin binding activity. Involved in several processes, including positive regulation of interleukin-1 production; positive regulation of protein secretion; and vesicle targeting, to, from or within Golgi. Acts upstream of or within negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process. Located in zymogen granule membrane. Part of gamma-secretase complex. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Orthologous to human TMED10 (transmembrane p24 trafficking protein 10). PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality before implantation. Heterozygous mice display abnormalities of the Golgi apparatus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
