Primary Identifier | MGI:1932093 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 81703 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; cAMP response element binding activity; and protein dimerization activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within with a negative effect on regulation of transcription by RNA polymerase II. Acts upstream of or within chromatin remodeling and negative regulation of fat cell differentiation. Located in nucleus. Is expressed in several structures, including blood island; central nervous system; genitourinary system; musculoskeletal system; and neural retina. Orthologous to human JDP2 (Jun dimerization protein 2). PHENOTYPE: Mice homozygous for a null allele exhibit increased white adipose tissue differentiation, short tail, and enhanced would healing due to increased cell proliferation. [provided by MGI curators] |