| Primary Identifier | MGI:1341859 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 14874 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable glutathione transferase activity; maleylacetoacetate isomerase activity; and protein homodimerization activity. Predicted to be involved in L-phenylalanine catabolic process and glutathione metabolic process. Predicted to act upstream of or within tyrosine catabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human GSTZ1 (glutathione S-transferase zeta 1). PHENOTYPE: Mice homozygous for disruptions in this gene have essentially normal phenotypes but do display ketoaciduria and severe sensitivity to diets high in tyrosine or phenylalanine. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
