| Primary Identifier | MGI:1096389 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 18191 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium channel regulator activity. Involved in modulation of chemical synaptic transmission; neurotransmitter receptor localization to postsynaptic specialization membrane; and postsynaptic density assembly. Acts upstream of or within neurotransmitter secretion and synapse assembly. Located in presynaptic membrane. Part of trans-synaptic protein complex. Is active in GABA-ergic synapse; glutamatergic synapse; and presynaptic active zone membrane. Is expressed in several structures, including inner ear; nervous system; neural retina; urinary system; and vibrissa. Human ortholog(s) of this gene implicated in alcohol dependence and nicotine dependence. Orthologous to human NRXN3 (neurexin 3). PHENOTYPE: Twenty percent of mice homozygous for a knock-out allele die postnatally prior to 20 days of age. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
