Primary Identifier | MGI:108031 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 14744 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including activation of GTPase activity; positive regulation of stress fiber assembly; and response to acidic pH. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human GPR65 (G protein-coupled receptor 65). PHENOTYPE: Homozygous mutant mice have thymocytes and splenocytes that are insensitive to pH-dependent cAMP production. [provided by MGI curators] |