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Protein Coding Gene : Foxn3 forkhead box N3
Primary Identifier  MGI:1918625 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  71375
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable DNA-binding transcription factor activity and cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within craniofacial suture morphogenesis. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; immune system; peripheral nervous system; and sensory organ. Orthologous to human FOXN3 (forkhead box N3).
PHENOTYPE: Hypomorphic homozygous knockout affects the expression of osteogenic genes and leads to craniofacial abnormalities and reduces pre- and postnatal survival. [provided by MGI curators]
  • synonyms:
  • forkhead box N3,
  • Foxn3,
  • Ches1,
  • MGI:2145044,
  • expressed sequence AW556347,
  • checkpoint supressor 1-like,
  • expressed sequence AA589593,
  • HTLFL1,
  • MGI:1276572,
  • Ches1l,
  • RIKEN cDNA 5430426H20 gene,
  • AA589593,
  • AW556347,
  • MGI:2144745,
  • 5430426H20Rik,
  • checkpoint suppressor 1
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