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Protein Coding Gene : Kcnk13 potassium channel, subfamily K, member 13
Primary Identifier  MGI:2384976 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  217826
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable identical protein binding activity; potassium channel activity; and protein heterodimerization activity. Involved in regulation of NLRP3 inflammasome complex assembly; regulation of excitatory synapse pruning; and regulation of resting membrane potential. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Is expressed in dentate gyrus subgranular zone and heart. Orthologous to human KCNK13 (potassium two pore domain channel subfamily K member 13).
PHENOTYPE: Homozygous knockout reduces the surveillance activity of microglial cells in the brain. [provided by MGI curators]
  • synonyms:
  • Kcnk13,
  • RIKEN cDNA F730021E22 gene,
  • LOC381712,
  • gene model 1685, (NCBI),
  • potassium channel, subfamily K, member 13,
  • MGI:2686416,
  • expressed sequence BB085247,
  • THIK-1,
  • BB085247,
  • MGI:2145065,
  • F730021E22Rik,
  • gene model 1570, (NCBI),
  • MGI:2686531,
  • LOC380778,
  • Gm1685,
  • Gm1570
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