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Protein Coding Gene : Moap1 modulator of apoptosis 1
Primary Identifier  MGI:1915555 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  64113
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable ubiquitin protein ligase binding activity. Involved in positive regulation of autophagosome assembly. Predicted to be located in cytosol; mitochondrial outer membrane; and nucleus. Is expressed in nervous system and sensory organ. Orthologous to human MOAP1 (modulator of apoptosis 1).
PHENOTYPE: Homozygous knockout mice show decreased sensitivity to Fas-mediated mitochondrial apoptosis of hepatocytes. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 9130023M10 gene,
  • 4930435G24Rik,
  • MGI:2144753,
  • 1700051B17Rik,
  • MGI:1925730,
  • 1700127I11Rik,
  • PNMA4,
  • MGI:1919571,
  • 9130023M10Rik,
  • expressed sequence AA987038,
  • 2510001G02Rik,
  • Moap1,
  • RIKEN cDNA 4930435G24 gene,
  • RIKEN cDNA 2510001G02 gene,
  • AA987038,
  • RIKEN cDNA 1700127I11 gene,
  • modulator of apoptosis 1,
  • RIKEN cDNA 1700051B17 gene,
  • MAP-1,
  • MGI:1923010,
  • MGI:1920710
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