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Protein Coding Gene : Asb2 ankyrin repeat and SOCS box-containing 2
Primary Identifier  MGI:1929743 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  65256
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable cullin family protein binding activity. Predicted to contribute to ubiquitin protein ligase activity. Involved in several processes, including heart development; podosome assembly; and skeletal muscle atrophy. Acts upstream of or within skeletal muscle cell differentiation. Located in Z disc. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut; heart; and musculature. Orthologous to human ASB2 (ankyrin repeat and SOCS box containing 2).
PHENOTYPE: Mice homozygous for a conditional cells activated in the immune system exhibit impaired immature dendritic cell migration. [provided by MGI curators]
  • synonyms:
  • MGI:1915827,
  • 1110008E15Rik,
  • RIKEN cDNA 1110008E15 gene,
  • Asb2,
  • ankyrin repeat and SOCS box-containing 2
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1 Involved In Mutations

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Canonical gene --> Exons in specific strains

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Features --> Overlapping features

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