Primary Identifier | MGI:1915399 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 68149 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable cysteine-type deubiquitinase activity and ubiquitin binding activity. Predicted to be involved in negative regulation of double-strand break repair and protein deubiquitination. Predicted to act upstream of or within proteolysis. Orthologous to human OTUB2 (OTU deubiquitinase, ubiquitin aldehyde binding 2). PHENOTYPE: Mice homozygous or heterozygous for a null mutation show increased incidence of chemically induced tumors. [provided by MGI curators] |