| Primary Identifier | MGI:2667725 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 217847 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable heparin binding activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in blood coagulation and liver regeneration. Predicted to be active in extracellular space. Is expressed in dorsal root ganglion; liver lobe; pancreas; and urinary system. Human ortholog(s) of this gene implicated in thrombophilia. Orthologous to human SERPINA10 (serpin family A member 10). PHENOTYPE: Mice homozygous for a knock-out allele display a reduced survival rate, enhanced thrombosis after ferric chloride-induced carotid artery injury, and increased mortality from pulmonary thromboembolism following collagen/epinephrine infusion. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
