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Protein Coding Gene : Eml1 echinoderm microtubule associated protein like 1
Primary Identifier  MGI:1915769 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  68519
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables microtubule binding activity. Involved in brain development; mitotic spindle organization; and neuroblast proliferation. Acts upstream of or within hematopoietic progenitor cell differentiation. Located in cytosol. Colocalizes with mitotic spindle midzone and mitotic spindle pole. Is expressed in liver; lung; nervous system; and retina. Used to study congenital nervous system abnormality and subcortical band heterotopia. Human ortholog(s) of this gene implicated in subcortical band heterotopia. Orthologous to human EML1 (EMAP like 1).
PHENOTYPE: Mice homozygous for a spontaneous mutation exhibit subcortical band heterotopia associated with seizures, developmental delay and behavioral deficits. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1110008N23 gene,
  • Expressed sequence AA171013,
  • A930030P13Rik,
  • AI853955,
  • expressed sequence AI853955,
  • AA171013,
  • ELP79,
  • MGI:2442730,
  • 1110008N23Rik,
  • MGI:2144910,
  • heterotopic cortex,
  • MGI:2144897,
  • MGI:5560738,
  • RIKEN cDNA A930030P13 gene,
  • Eml1,
  • expressed sequence AI847476,
  • echinoderm microtubule associated protein like 1,
  • AI847476,
  • MGI:2445787,
  • heco
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