Primary Identifier | MGI:2656842 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 353326 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in several processes, including placenta development; skeletal muscle satellite cell proliferation; and skeletal muscle tissue development. Acts upstream of or within angiogenesis and labyrinthine layer development. Is active in Z disc. Is expressed in several structures, including diaphragm; genitourinary system; immune system; musculature; and neocortex layer. Orthologous to human RTL1 (retrotransposon Gag like 1). PHENOTYPE: Mice heterozygous for a paternally inherited knock-out allele exhibit fetal/neonatal lethality associated with underdevelopment of the placenta. Mice heteroygous for a maternally inherited knock-out allele exhibit neonatal lethality and decreased survival associated with placental overdevelopment. [provided by MGI curators] |