| Primary Identifier | MGI:106340 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 217864 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity; enzyme binding activity; and transcription corepressor activity. Involved in erythrocyte differentiation; negative regulation of gene expression; and positive regulation of megakaryocyte differentiation. Predicted to be located in nucleoplasm. Predicted to be part of DNA repair complex; histone deacetylase complex; and transcription repressor complex. Is expressed in several structures, including brain; early embryo; extraembryonic component; liver; and nose. Orthologous to human RCOR1 (REST corepressor 1). PHENOTYPE: Mice homozygous for a null allele exhibit partial embryonic lethality, defective embryonic erythropoiesis, and decreased erythroid progenitor cell number. No homozygotes survive to P7. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
