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Protein Coding Gene : Tnfaip2 tumor necrosis factor, alpha-induced protein 2
Primary Identifier  MGI:104960 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  21928
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization and exocytosis. Predicted to be part of exocyst. Is expressed in several structures, including embryo mesenchyme; future brain; genitourinary system; immune system; and sensory organ. Used to study focal segmental glomerulosclerosis. Orthologous to human TNFAIP2 (TNF alpha induced protein 2).
PHENOTYPE: Homozygous null mice develop albuminuria, podocyte injury, with mitochondrial abnormalities and progressive focal segmental glomerulosclerosis. [provided by MGI curators]
  • synonyms:
  • Tnfip2,
  • tumor necrosis factor, alpha-induced protein 2,
  • tumor necrosis factor alpha induced protein 2,
  • Exoc3l3,
  • MGD-MRK-15152,
  • tumor necrosis factor induced protein 2,
  • M-sec,
  • MGD-MRK-31033,
  • Tnfaip2
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