Primary Identifier | MGI:88407 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 12709 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables creatine kinase activity. Involved in futile creatine cycle. Located in myelin sheath. Is active in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; musculature; and sensory organ. Orthologous to human CKB (creatine kinase B). PHENOTYPE: Homozygous null mice have abnormal hippocampal morphology with enlarged mossy fiber field size and display resistance to pharmacologically induced seizures, reduced habituation and spatial learning impairments. [provided by MGI curators] |