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Protein Coding Gene : Zfyve21 zinc finger, FYVE domain containing 21
Primary Identifier  MGI:1915770 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  68520
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable metal ion binding activity. Predicted to be located in endosome and focal adhesion. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and liver and biliary system. Orthologous to human ZFYVE21 (zinc finger FYVE-type containing 21).
PHENOTYPE: Mice with induced loss of expression in endothelial cells show impaired vascular barrier functions, reduced glomerular filtration rates, and decreased weight gain. [provided by MGI curators]
  • synonyms:
  • AW558780,
  • Zfyve21,
  • MGI:2145117,
  • C85416,
  • MGI:2145050,
  • RIKEN cDNA 1110013H04 gene,
  • 1110013H04Rik,
  • expressed sequence AW558780,
  • expressed sequence C85416,
  • zinc finger, FYVE domain containing 21
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