Primary Identifier | MGI:1890220 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 56696 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity. Involved in negative regulation of G2/M transition of mitotic cell cycle. Acts upstream of or within G1/S transition of mitotic cell cycle. Predicted to be located in plasma membrane. Is expressed in cerebral cortex; long bone epiphyseal plate; and thymus primordium. Used to study autoimmune disease. Orthologous to human GPR132 (G protein-coupled receptor 132). PHENOTYPE: Mice homozygous for disruptions in this gene display a generally normal phenotype but eventually develop a "late onset lymphoproliferative autoimmune syndrome" [provided by MGI curators] |