Primary Identifier | MGI:107166 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 22355 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity and peptide hormone binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and negative regulation of smooth muscle cell proliferation. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; respiratory system; retina; and skeleton. Orthologous to human VIPR2 (vasoactive intestinal peptide receptor 2). PHENOTYPE: Homozygotes for a targeted null mutation exhibit enhanced delayed-type hypersensitivity (type IV) and reduced immediate-type hypersensitivity (type I). [provided by MGI curators] |