Primary Identifier | MGI:1261845 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 52635 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity; identical protein binding activity; and phospholipid binding activity. Predicted to be involved in endocytosis; endoplasmic reticulum-plasma membrane tethering; and lipid transport. Predicted to be located in cytoplasmic side of plasma membrane; cytosol; and endoplasmic reticulum-plasma membrane contact site. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including aorta; genitourinary system; mammary gland; nervous system; and retina. Orthologous to human ESYT2 (extended synaptotagmin 2). PHENOTYPE: Mice are viable and fertile without overt morphological defects except reduced FGF-stimulated mouse embryonic fibroblast migration. [provided by MGI curators] |