| Primary Identifier | MGI:2443471 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 320145 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic limb morphogenesis. Acts upstream of or within dorsal/ventral pattern formation and proximal/distal pattern formation. Predicted to be located in nucleus. Is expressed in several structures, including branchial arch; embryo ectoderm; limb bud; nose; and primitive streak. Orthologous to human SP8 (Sp8 transcription factor). PHENOTYPE: Homozygous mutant fetuses are characterized by truncated limbs, the lack of a tail, abnormal craniofacial development, and neural tube defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
