| Primary Identifier | MGI:1338035 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 320910 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable extracellular matrix protein binding activity and integrin binding activity. Acts upstream of or within several processes, including Langerhans cell differentiation; hard palate development; and transforming growth factor beta receptor signaling pathway. Part of integrin alphav-beta8 complex. Is expressed in several structures, including alimentary system; male reproductive system; nervous system; sensory organ; and skeleton. Orthologous to human ITGB8 (integrin subunit beta 8). PHENOTYPE: Mice homozygous for disruption of this gene either die before E11.5 as a result of circulatory abnormalities in the placenta or die within the first for days after birth and display intracerebral hemorrhaging. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
