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Protein Coding Gene : Gdi2 GDP dissociation inhibitor 2

Primary Identifier  MGI:99845 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  14569
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Contributes to GTPase activator activity. Acts upstream of or within small GTPase-mediated signal transduction. Located in Golgi apparatus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human GDI2 (GDP dissociation inhibitor 2).
PHENOTYPE: Knock-out results in embryonic lethality between E10.5 to E14.5, with extensive cell death and cell loss is embryos and increased apoptosis in E12.5 livers. [provided by MGI curators]
  • synonyms:
  • GDI-B,
  • GDI beta,
  • MGD-MRK-16636,
  • GDP dissociation inhibitor 2,
  • Gdi2,
  • guanosine diphosphate (GDP) dissociation inhibitor 3,
  • Gdi3,
  • MGD-MRK-33618,
  • GDIB,
  • MGI:105939

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For