| Primary Identifier | MGI:1932970 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 83428 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable corticotropin-releasing hormone receptor binding activity. Acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in axon terminus and varicosity. Predicted to be active in extracellular space. Is expressed in brain; ileum; male reproductive gland or organ; and pancreas. Orthologous to human UCN3 (urocortin 3). PHENOTYPE: Mice homozygous for one null allele are protected from the hyperinsulinemia, hyperglycemia, glucose intolerance, hepatic steatosis and hypertriglyceridemia induced by a high-fat diet, and show better glucose tolerance as they age. Mice homozygous for another null allele show improved social memory. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
