Primary Identifier | MGI:96570 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 16323 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables signaling receptor binding activity. Involved in eyelid development in camera-type eye; positive regulation of DNA-templated transcription; and positive regulation of ovulation. Acts upstream of or within several processes, including Sertoli cell differentiation; positive regulation of transcription by RNA polymerase II; and steroid metabolic process. Located in perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; embryo mesenchyme; heart; reproductive system; and skeleton. Orthologous to human INHBA (inhibin subunit beta A). PHENOTYPE: Homozygotes for a targeted null mutation lack vibrissae and lower incisors, have defects in their secondary palates, and die shortly after birth. [provided by MGI curators] |