| Primary Identifier | MGI:1919989 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 72739 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in lysosome organization; negative regulation of metabolic process; and regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleoplasm. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and retina nuclear layer. Orthologous to human ZKSCAN3 (zinc finger with KRAB and SCAN domains 3) and ZKSCAN4 (zinc finger with KRAB and SCAN domains 4). PHENOTYPE: Mice homozygous for a null allele exhibit normal weight, size, appearance and autophagy response to starvation and re-feeding. Mice homozygous for a different null allele exhibit increased P. aeruginosa strain K killing in the lungs. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
