| Primary Identifier | MGI:3606486 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 238555 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable signaling receptor binding activity. Involved in negative regulation of activated T cell proliferation and negative regulation of cytokine production. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle; negative regulation of signal transduction; and positive regulation of regulatory T cell differentiation. Located in cell surface. Orthologous to several human genes including BTN2A2 (butyrophilin subfamily 2 member A2). PHENOTYPE: Mice homozygous for a null allele exhibit enhanced effector CD4+ and CD8+ T cell responses, exacerbated experimental autoimmune encephalomyelitis, and anti-tumor immune responses. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
