Primary Identifier | MGI:1931523 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 80838 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity and heparin binding activity. Involved in positive regulation of receptor-mediated endocytosis. Acts upstream of or within spermatogenesis. Located in cell surface; nucleus; and vesicle. Is expressed in brain; cerebral cortex; forebrain; telencephalon mantle layer; and telencephalon ventricular layer. Orthologous to human H1-1 (H1.1 linker histone, cluster member). PHENOTYPE: Mice homozygous for a targeted null mutation are viable, fertile and do not exhibit any defects in the reproductive system or in spermatogenesis. Female mice homozygous for a null allele exhibit reduced litter size due to abnormal preimplantation development. [provided by MGI curators] |