Primary Identifier | MGI:2652818 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 195208 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable kinesin binding activity. Acts upstream of or within generation of neurons; glutamatergic synaptic transmission; and neuronal action potential. Predicted to be located in cilium; cytosol; and microtubule cytoskeleton. Predicted to be active in cytoskeleton and kinocilium. Is expressed in several structures, including alimentary system; brain; lung; mesonephros; and metanephros. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autosomal recessive nonsyndromic deafness 66; dyslexia; nephronophthisis 19; and sclerosing cholangitis. Orthologous to human DCDC2 (doublecortin domain containing 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired short term object recognition, impaired visuo-spatial learning and memory and increased anxiety-related response. [provided by MGI curators] |