| Primary Identifier | MGI:104513 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 18105 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including anion binding activity; dihydronicotinamide riboside quinone reductase activity; and melatonin binding activity. Predicted to be involved in several processes, including positive regulation of ERK1 and ERK2 cascade; positive regulation of vascular associated smooth muscle cell proliferation; and quinone catabolic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in adenohypophysis. Human ortholog(s) of this gene implicated in Parkinson's disease; agranulocytosis; breast cancer; and breast carcinoma. Orthologous to human NQO2 (N-ribosyldihydronicotinamide:quinone dehydrogenase 2). PHENOTYPE: Mice homozygouse for disruptions in this gene have an essentially normal phenotype but with abnormalities in WBC counts and increased susceptibility to chemically induced tumors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
