| Primary Identifier | MGI:1921395 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 74145 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-glutamine gamma-glutamyltransferase activity. Involved in blood coagulation, fibrin clot formation. Acts upstream of or within blood coagulation and peptide cross-linking. Located in collagen-containing extracellular matrix. Is expressed in several structures, including alimentary system; hemolymphoid system; limb; nervous system; and reproductive system. Used to study factor XIII deficiency. Human ortholog(s) of this gene implicated in artery disease (multiple); factor XIII deficiency; priapism; and thrombophilia (multiple). Orthologous to human F13A1 (coagulation factor XIII A chain). PHENOTYPE: Homozygous mutant mice exhibit bleeding symptoms, increased lethality, and impaired fertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
