Primary Identifier | MGI:1321404 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 17084 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within positive regulation of lipopolysaccharide-mediated signaling pathway. Predicted to be located in extracellular region. Is expressed in cerebral cortex; genitourinary system; and lower leg bone. Orthologous to human LY86 (lymphocyte antigen 86). PHENOTYPE: Mice homozygous for a knock-out allele display impaired LPS-induced B-cell proliferation and antibody production. [provided by MGI curators] |