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Protein Coding Gene : Riok1 RIO kinase 1
Primary Identifier  MGI:1918590 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  71340
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in maturation of SSU-rRNA and positive regulation of rRNA processing. Predicted to be part of methyltransferase complex and preribosome, small subunit precursor. Predicted to be active in cytosol. Is expressed in embryo; extraembryonic component; oocyte; primitive endoderm; and yolk sac. Orthologous to human RIOK1 (RIO kinase 1).
PHENOTYPE: Mice homozygous for a knock-out allele show normal blastocyst formation but exhibit complete embryonic lethality prior to organogenesis. [provided by MGI curators]
  • synonyms:
  • 3110046C13Rik,
  • 5430416A05Rik,
  • RIKEN cDNA 5430416A05 gene,
  • RIKEN cDNA 3110046C13 gene,
  • Riok1,
  • MGI:1920472,
  • MGI:2145325,
  • RIO kinase 1,
  • AL033302,
  • expressed sequence AL033302
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1 Involved In Mutations

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Disease

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