Primary Identifier | MGI:88182 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 12161 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable BMP receptor binding activity; protein heterodimerization activity; and receptor ligand activity. Involved in several processes, including multicellular organismal-level iron ion homeostasis; positive regulation of signal transduction; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including BMP signaling pathway; endochondral ossification; and male genitalia development. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; female reproductive system; skeleton; and visual system. Orthologous to human BMP6 (bone morphogenetic protein 6). PHENOTYPE: One homozygous null mutant showed delayed ossification in the developing sternum while females of a second null mutant were smaller than normal in size. [provided by MGI curators] |