Primary Identifier | MGI:1928741 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 56705 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable small GTPase binding activity. Predicted to be involved in cytoskeleton organization and negative regulation of ERK1 and ERK2 cascade. Located in cytoplasm. Is expressed in cerebral cortex intermediate zone; cerebral cortex subventricular zone; cerebral cortex ventricular layer; and palatal shelf. Orthologous to human RANBP9 (RAN binding protein 9). PHENOTYPE: Mice homozygous for a null mutation display partial neonatal lethality. Survivors display infertility with impaired spermatogenesis and oogenesis, azoospermia and premature ovarian failure. [provided by MGI curators] |