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Protein Coding Gene : Dek DEK proto-oncogene
Primary Identifier  MGI:1926209 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  110052
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable histone binding activity. Acts upstream of or within regulation of double-strand break repair via nonhomologous end joining. Located in contractile muscle fiber and nucleus. Is expressed in several structures, including early conceptus; limb; oocyte; retina; and telencephalon. Orthologous to human DEK (DEK proto-oncogene).
PHENOTYPE: Mice homozygous for a null allele exhibit delayed development of DMBA- and TPA-induced papillomas. [provided by MGI curators]
  • synonyms:
  • DEK proto-oncogene (DNA binding),
  • D13H6S231E,
  • MGI:89627,
  • MGD-MRK-3410,
  • MGI:1914254,
  • Dek,
  • 1810019E15Rik,
  • RIKEN cDNA 1810019E15 gene,
  • DEK proto-oncogene,
  • DNA segment, Chr 13, human D6S231E
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

1 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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