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Protein Coding Gene : Rnf144b ring finger protein 144B

Primary Identifier  MGI:2384986 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  218215
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of apoptotic process and ubiquitin-dependent protein catabolic process. Predicted to be part of ubiquitin ligase complex. Predicted to be active in mitochondrial membrane. Is expressed in several structures, including bladder; cranium; hindbrain ventricular layer; jaw; and thoracic segment skeleton. Orthologous to human RNF144B (ring finger protein 144B).
PHENOTYPE: Homozygous null mice exhibit decreased susceptibility to encephalomyocarditis virus (EMCV) infection and higher survival rate and MEFs show impaired vesicular stomatitis virus replication. [provided by MGI curators]
  • synonyms:
  • ring finger protein 144B,
  • cDNA sequence BC025007,
  • BC025007,
  • Rnf144b,
  • RIKEN cDNA E130105P19 gene,
  • IBR domain containing 2,
  • E130105P19Rik,
  • MGC:32473,
  • Ibrdc2,
  • MGI:2444745

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For