Primary Identifier | MGI:103124 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 12022 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including endothelial cell differentiation; negative regulation of Wnt signaling pathway; and spleen development. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; limb; and sensory organ. Orthologous to human BARX1 (BARX homeobox 1). PHENOTYPE: Mice homozygous for a null mutation die around E13 embryonic stage with shrunken and malformed stomach or shortly after birth with cleft palate and abnormal tooth development depending on strain background. [provided by MGI curators] |