| Primary Identifier | MGI:1922670 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 75420 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ribonucleoprotein complex binding activity and selenocysteine insertion sequence binding activity. Acts upstream of or within several processes, including forebrain development; negative regulation of mRNA catabolic process; and selenocysteine incorporation. Located in mitochondrion. Part of ribonucleoprotein complex. Is expressed in cerebellum; retina inner nuclear layer; and retina outer nuclear layer. Human ortholog(s) of this gene implicated in thyroid gland disease. Orthologous to human SECISBP2 (SECIS binding protein 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete preweaning lethality while heterozygotes exhibit reduced serum selenium levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
