| Primary Identifier | MGI:108482 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 15466 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable heterocyclic compound binding activity; histamine receptor activity; and neurotransmitter receptor activity. Acts upstream of or within several processes, including epithelial cell morphogenesis; gastric acid secretion; and learning or memory. Predicted to be active in dendrite and plasma membrane. Is expressed in brain; early conceptus; stomach; and uterus. Orthologous to human HRH2 (histamine receptor H2). PHENOTYPE: Homozygotes for a targeted null mutation exhibit enlarged folds in gastric mucosa, elevated serum gastrin levels, increased numbers of parietal and enterochromaffin-like cells, and lack of secretion of gastric acid in response to histamine or gastrin. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
