|  Help  |  About  |  Contact Us

Protein Coding Gene : Thoc3 THO complex 3

Primary Identifier  MGI:1920916 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  73666
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable RNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nuclear speck. Predicted to be part of THO complex part of transcription export complex. Predicted to colocalize with chromosome, telomeric region. Orthologous to human THOC3 (THO complex subunit 3).
PHENOTYPE: Mice homozygous for a knock-out allele show failure of morula compaction and complete embryonic lethality prior to organogenesis. In vitro outgrowth assays show that embryos hatch from the zona pellucida but form atypical outgrowths with an abnormal inner cell mass and few trophectoderm cells. [provided by MGI curators]
  • synonyms:
  • AL033344,
  • Thoc3,
  • THO complex 3,
  • 2410044K02Rik,
  • MGI:2145327,
  • RIKEN cDNA 2410044K02 gene,
  • expressed sequence AL033344

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For