Primary Identifier | MGI:1889011 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 104069 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity and tubulin binding activity. Involved in synaptic vesicle endocytosis. Acts upstream of or within several processes, including chemical synaptic transmission; dopamine metabolic process; and negative regulation of neuron apoptotic process. Located in synapse. Is expressed in central nervous system; peripheral nervous system; retina; stomach; and testis. Human ortholog(s) of this gene implicated in Lewy body dementia and Parkinson's disease. Orthologous to human SNCB (synuclein beta). PHENOTYPE: Mice homozygous for disruptions in this gene display an essentially normal phenotype. [provided by MGI curators] |