Primary Identifier | MGI:103185 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 20184 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables nuclear retinoid X receptor binding activity. Predicted to be involved in several processes, including DNA repair-dependent chromatin remodeling; mitotic G2 DNA damage checkpoint signaling; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in nuclear body. Predicted to be part of BRCA1-A complex. Predicted to be active in site of double-strand break. Orthologous to human UIMC1 (ubiquitin interaction motif containing 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit premature death due to B-cell lymphomas and abnormal DNA repair. [provided by MGI curators] |