| Primary Identifier | MGI:2178800 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 75477 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin binding activity. Predicted to be involved in positive regulation of actin filament bundle assembly and regulation of actin filament polymerization. Predicted to be located in cytoskeleton and nucleus. Predicted to be active in cytoplasm. Orthologous to human PFN3 (profilin 3). PHENOTYPE: Nullizygous mutations of this gene cause male subfertility, reduced sperm count/vitality, asthenozoospermia, globozospermia, deformed sperm flagella and impaired spermiogenesis associated with defects in acrosome biogenesis, autophagy, manchette development and mitochondrial organization. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
