| Primary Identifier | MGI:1351490 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 27261 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within Ras protein signal transduction. Located in cytoplasm. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human DOK3 (docking protein 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased incidence of lung adenocarcinomas. Mice for another null alelle show increased IgM antibodies and have enchanced humoral immune responses to T cell-independent type I and II antigens. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
