Primary Identifier | MGI:1924106 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 76856 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables voltage-gated calcium channel activity. Acts upstream of or within several processes, including flagellated sperm motility; sodium ion transport; and sperm capacitation. Located in acrosomal vesicle and endoplasmic reticulum. Part of CatSper complex. Is expressed in ductus deferens; epididymis; ileum; prostate gland; and testis. Orthologous to human CATSPER3 (cation channel sperm associated 3). PHENOTYPE: Mice homozygous for this mutation are viable and exhibit no gross physical or behavioral abnormality. Although wild-type and homozygous mutant females bred to wild-type males exhibit similar fertility, male homozygotes are infertile. [provided by MGI curators] |