| Primary Identifier | MGI:107754 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 18014 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables E-box binding activity and chromatin binding activity. Involved in positive regulation of DNA-binding transcription factor activity; positive regulation of neuron differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including inner ear morphogenesis; positive regulation of exit from mitosis; and regulation of neuron differentiation. Located in perikaryon. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; neurogenic placode; and sensory organ. Orthologous to human NEUROG1 (neurogenin 1). PHENOTYPE: Homozygotes for a targeted null mutation exhibit defects in midbrain, dorsal root sensory ganglia and a subset of cranial ganglia. Mutants are born alive, but fail to nurse, and die within 12 hours. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
