Primary Identifier | MGI:1922300 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 75050 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in cilium assembly. Acts upstream of or within epithelial cilium movement involved in extracellular fluid movement; establishment of localization in cell; and ventricular system development. Located in cilium. Is expressed in several structures, including choroid plexus; floor plate; genitourinary system; liver; and spleen. Used to study hydrocephalus. Orthologous to human KIF27 (kinesin family member 27). PHENOTYPE: Homozygous mice are small and die by 8 weeks and exhibit hydrocephalus, rhinitis and otitis media. [provided by MGI curators] |